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Botulinum toxin may directly reduce depression by altering brain activity

Discover how botulinum toxin injections in the glabella affect brain function, enhancing mood by altering emotional feedback from frowning.

Suboptimal Screening for Albuminuria

Expert discusses how, despite its importance, albuminuria screening remains underutilized, and improving adherence to dual testing can transform early CKD detection.

Introduction to Nonfactor Therapies

Exploration of the emergence of nonfactor treatment classes, explaining how these agents function independently of missing clotting factors and their relevance to patient convenience, dosing, and efficacy.

Implications of the EMERALD Study for Patients, Providers, and Payers

The EMERALD study carries significant implications across multiple stakeholders in ER+/HER2- metastatic breast cancer.

Exploring the Stages of CKD

Expert discusses how understanding and promoting awareness of CKD stages enables earlier intervention and better management of disease progression and cardiovascular risk.

The Evolution of Factor Replacement Therapy

A historical perspective on traditional factor replacement therapies, tracing their development, successes, and ongoing limitations such as short half-life, infusion requirements, and inhibitor formation.

Prevalence of Decreased eGFR and Elevated uACR

Expert discusses how the high prevalence of undiagnosed CKD creates a significant clinical and financial burden that can be alleviated through earlier detection and intervention.

Health Plans Beware: Keep Contract Language Tight If Your PBM Wants Rebate Guarantees Renegotiated Because of the IRA and Biosimilars | AMCP Nexus 2025

Milliman’s Jennifer Cruz says plans are losing rebates because of steep price discounts negotiated under the Inflation Reduction Act. but that they need to be sure that renegotiation of rebate guarantees doesn’t get too broad.

PBMs Make a Case for the GLP-1 Teeter Totter: Up on the Pharmacy Benefit, Down on the Medical One | AMCP Nexus 2025

Pharmacy benefit managers are approaching health plans with value-based contracts that consider lower costs on the medical benefit of the insurance, says Jennifer Cruz of Milliman.

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