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New drug class shows promise for geographic atrophy

Kamuvudines are a new class of drugs that are derived from the anti-HIV nucleoside reverse transcriptase inhibitors. They are designed to inhibit the inflammasome, part of the innate immune system that is triggered in geographic atrophy.

CMS negotiates a 70% discount for Ozempic and Wegovy

CMS has released the negotiated prices for the second set of drugs for Medicare Part D through the Inflation Reduction Act. Discounts range from 38% for Austedo and Austedo XR to 85% for Janumet and Janumet XR.

Louisiana Surgeon General Ralph Abraham named CDC principal deputy amid vaccine trust concerns

Ralph Abraham's appointment as CDC's principal deputy director raises concerns over vaccine trust and public health amid political pressures and misinformation.

Virtual care replaces, not adds, Medicare visits for health systems, analysis shows

Telehealth mostly replaces in-person visits, with a 74% substitution rate, indicating lower federal costs and sustained value beyond the pandemic.

FDA approves $2.59 million gene therapy for SMA

Itvisma is a one-time gene therapy approved for both children and adults with spinal muscular atrophy. It will be available in December.

Orphan Drug Loophole Shields Blockbuster Drugs From Price Negotiations

A provision in the One Big Beautiful Bill delays or exempts high-spending medications with orphan indications from Medicare drug price negotiations.

New blood test tool, app could help detect tuberculosis early in low-resource areas, according to new study in China

A new blood test and app combination enhances tuberculosis screening in China, enabling early detection and cost-effective solutions in resource-limited areas.

A first for radiation oncology: new ASTRO guideline focuses on radiation therapy for gastric cancer

ASTRO's new guidelines enhance radiation therapy strategies for gastric cancer, improving treatment outcomes and patient care across various stages of the disease.

How health systems can integrate tobacco-cessation interventions for HIV, tuberculosis patients

Nicotine dependency is a worldwide health threat, especially for HIV patients, who are more likely to smoke and to have health complications than healthy patients.

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