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How new psoriasis, alopecia and atopic dermatitis therapies stood out at Fall Clinical Derm 2025

Discover groundbreaking advancements in dermatology from the 2025 Fall Clinical Conference, featuring innovative treatments for psoriasis, alopecia, and atopic dermatitis.

Phase 3 trial launches for novel antibody targeting integrin beta-6 in advanced lung cancer

Pfizer’s sigvotatug vedotin combined with Keytruda is being studied in patients with non-small cell lung cancer. Researchers suggest sigvotatug vedotin’s ability to induce immunogenic cell death may enhance antitumor activity.

The FDA proposes ditching comparative efficacy studies for biosimilars

To gain approvals, biosimilar manufacturers could do faster, less expensive analytical studies of their products' composition.

A conversation with Leslie T. Busby, M.D.: Perspectives on oncology practice, value-based care and policy challenges

The medical director The US Oncology Network discusses adherence to clinical pathways, CAR-T therapy and concerns about the consequences of drug price negotiation under the IRA.

NIH’s investigational AI technology unlocks faster, clearer retinal imaging with 75% less data

The Residual Transformer Generative Adversarial Network (RRTGAN) generates high-quality, cellular-level retinal images from minimal data inputs, overcoming the limitations of previous slow and burdensome imaging methods.

Metabolite study links blood molecules to excessive daytime sleepiness

The findings challenge the conventional view that daytime sleepiness is always a result of insufficient sleep, poor sleep hygiene or classic sleep disorders.

Atopic dermatitis care advances in 2025 with new biologics, topicals and oral therapies

In 2025, atopic dermatitis care evolved with new treatments, prioritizing holistic methods and personalized strategies for improved patient outcomes.

UC Davis develops new drug for bladder cancer patients

Researchers used nanoparticle technology to encapsulate paclitaxel and target bladder tumors more effectively. Early results demonstrate tumor elimination and minimal side effects.

Kyverna to submit BLA for investigational CAR-T therapy for stiff-person syndrome

Kyverna’s investigational CAR-T therapy, mivocabtagene autoleucel (miv-cel) showed clinically meaningful mobility improvements in most stiff-person syndrome patients, prompting the company to plan an FDA BLA submission in 2026.

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